Tributes to Dale Coln, MD, upon his retirement.
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منابع مشابه
A natively unfolded toxin domain uses its receptor as a folding template.
Natively unfolded proteins range from molten globules to disordered coils. They are abundant in eukaryotic genomes and commonly involved in molecular interactions. The essential N-terminal translocation domains of colicin toxins from Escherichia coli are disordered bacterial proteins that bind at least one protein of the Tol or Ton family. The colicin N translocation domain (ColN-(1-90)), which...
متن کاملThe antibacterial toxin colicin N binds to the inner core of lipopolysaccharide and close to its translocator protein
Colicins are a diverse family of large antibacterial protein toxins, secreted by and active against Escherichia coli and must cross their target cell's outer membrane barrier to kill. To achieve this, most colicins require an abundant porin (e.g. OmpF) plus a low-copy-number, high-affinity, outer membrane protein receptor (e.g. BtuB). Recently, genetic screens have suggested that colicin N (Col...
متن کاملAntibacterial toxin colicin N and phage protein G3p compete with TolB for a binding site on TolA
Most colicins kill Escherichia coli cells by membrane pore formation or nuclease activity and, superficially, the mechanisms are similar: receptor binding, translocon recruitment, periplasmic receptor binding and membrane insertion. However, in detail, they employ a wide variety of molecular interactions that reveal a high degree of evolutionary diversification. Group A colicins bind to members...
متن کاملDale J. Benos, Ph.D. (1950-2010).
THE UNIVERSITY OF ALABAMA AT BIRMINGHAM, the American Physiological Society, and physiologists all over the world were stunned by the untimely passing of Dale J. Benos on October 7th, 2010 (Fig. 1). In his memorial service, held November 12th, 2010 at the University of Alabama at Birmingham, a number of distinguished scientists, educators and administrators, and medical students delivered movin...
متن کاملReaction Kinetics and Mechanistic Studies of Nitric Oxide Removal by Combined Persulfate and Ferrous-edta Systems
Md Arif Khan obtained his BS in chemical engineering from Bangladesh University of Engineering and Technology (BUET) in 2008. Arif is currently a Chemical Engineering graduate student at North Carolina A&T State University. He completed his coursework in 2012, and is working on his thesis entitled: “Chemical Reactive Separations in Energy and Environmental Processes”, under the supervision of D...
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عنوان ژورنال:
- Proceedings
دوره 18 4 شماره
صفحات -
تاریخ انتشار 2005